Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.Īnti-Gonadotropin-Releasing Hormone Antibody, NT, clone HU11B (Ascites Free) is an antibody against Gonadotropin-Releasing Hormone for use in Immunohistochemistry (Paraffin), Affinity Binding Assay, Immunofluorescence, Electron Microscopy. LHRH-producing neurons are located mainly in the lateral anterior hypothalamus, septum, and medial preoptic area, from where they extend axons towards the median eminence and relese the hormone into the hypothalamo-hypophyseal portal blood vessels in an episodic or pulsatile manner. It plays a primary neuroendocrine role in orchestrating the developmental processes associated with sexual development in immature mammals and also in maintaining normal reproductive function in adults.
The LHRH decapeptide functions as the primary endocrine link between the brain and the reproductive system. prolactin release-inhibiting factor 1 (a.a. 22-90), which is further processed by a proteolytic cleavage to release the GnRH/LHRH decapeptide (a.a. GnRH/LHRH is initially produced as a 90-amino acid progonadoliberin-1 precursor protein (UniProt P13562), removal of the signal peptide (a.a. Gonadotropin-releasing hormone I (also known as GnRH, GnRH-I, Gonadoliberin-1, Gonadoliberin I, LHRH, LH-RH I, Luteinizing hormone-releasing hormone I) is encoded by the Gnrh1 (also known as Gnrh, Lhrh1, Lnrh) gene (Gene ID 14714) in murine species.
Luteinizing hormone-releasing hormone I.
kláve Species ReactivityĪnti-Gonadotropin-Releasing Hormone Antibody, NT, clone HU11B (Ascites Free) 100% Performance Guaranteed Tabulka spec.
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